The Role of Inflammatory Markers for Risk Stratification and Prognosis in Dialysis Patients: A Narrative Review

Authors

  • Siti Liyana Mohd Nor Faculty of Medicine and Health Sciences, Universiti Sains Islam Malaysia, Nilai, 71800, Malaysia.
  • Mohd Radzniwan A. Rashid Department of Primary Care, Faculty of Medicine and Health Sciences, Universiti Sains Islam Malaysia, 71800, Malaysia.
  • Faizul Helmi Addnan Faculty of Medicine and Health Sciences, Universiti Sains Islam Malaysia, Nilai, 71800, Malaysia.
  • Siva Gowri Pathmanathan Faculty of Medicine and Health Sciences, Universiti Sains Islam Malaysia, Nilai, 71800, Malaysia.
  • Nizam Baharom Department of Primary Care, Faculty of Medicine and Health Sciences, Universiti Sains Islam Malaysia, 71800, Malaysia.
  • Sharifah Najwa Syed Mohamad Department of Primary Care, Faculty of Medicine and Health Sciences, Universiti Sains Islam Malaysia, 71800, Malaysia.
  • Ruslinda Mustafar Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras,56000 Kuala Lumpur, Malaysia.
  • Saharudin Ahmad Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras,56000 Kuala Lumpur, Malaysia.
  • Arifa Mustika Department of Anatomy, Histology, Faculty of Medicine, Universitas Airlangga, Surabaya, 60115, Indonesia.
  • Minidian Fasitasari Medical Faculty of Universitas Islam Sultan Agung, Semarang, 50112, Indonesia.
  • Lusito Lusito Medical Faculty of Universitas Islam Sultan Agung, Semarang, 50112, Indonesia.

DOI:

https://doi.org/10.33102/mjosht.493

Keywords:

dialysis, inflammatory markers, risk stratification, prognosis, cardiovascular complication

Abstract

Chronic inflammation is a prevalent condition among dialysis patients and is associated with adverse health outcomes. This narrative review aims to provide a comprehensive analysis of the types and roles of inflammatory markers in risk assessment and their impact on the prognosis of dialysis patients. The associations between various inflammatory markers, including C-Reactive Protein (CRP), anti-inflammatory markers (IL-4, IL-10), and pro-inflammatory markers (TNF-α, IL-1, IL-6, IL-12), are evaluated in relation to their ability to predict mortality and cardiovascular complications in this population. Additionally, the potential of these markers for individualized risk stratification is discussed, aiding proper clinical decision-making and improving patient care. This review synthesizes current knowledge on inflammatory markers and their impact on the outcomes of dialysis patients, offering insights for improved prognostic assessment and therapeutic strategies.

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2025-10-14

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Medical and Health Sciences

How to Cite

The Role of Inflammatory Markers for Risk Stratification and Prognosis in Dialysis Patients: A Narrative Review. (2025). Malaysian Journal of Science Health & Technology, 11(2), 236-248. https://doi.org/10.33102/mjosht.493

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