Acute Ischaemic Stroke in a COVID-19 Patient on Baricitinib - A Causal Effect or a Multifactorial Relationship?
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https://doi.org/10.33102/mjosht.v8i.265Keywords:
Ischaemic Stroke, COVID-19, Arterial Thrombosis, BaricitinibAbstract
Coronavirus disease 2019 (COVID-19), a multisystemic disorder caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been associated with both venous and arterial thromboses. The hypercoagulable state of the disease poses a challenge to the patient’s management. We herein report a case of acute ischaemic stroke in a COVID-19 patient who had been treated with three days of Baricitinib, an immunotherapy that can potentially augment the thrombotic risks. The case highlights the dilemma faced when initiating immunotherapy in a COVID-19 patient and emphasises the importance of evaluating the patient’s thrombotic risks, balanced against the benefit of immunotherapy, to facilitate the selection of ideal candidates for the immunotherapy.
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Copyright (c) 2022 Wei Ming Tan, Hana Maizuliana Solehan, Sarah Zulaikha Samad, M Firdaus A Bakar, Nor Safiqah Sharil, Nur Ezzaty Mohammad Kazmin, Fatimah Zanirah, Koon Ket Sia
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