Hyperprolactinaemia in a Patient with Acute Ischaemic Stroke


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Authors

  • Wan Mohd Saifuhisam Wan Zain
  • Julia Omar
  • Tuan Salwani Tuan Ismail
  • Nor Azlin Azraini Che Soh Che Soh

DOI:

https://doi.org/10.33102/mjosht.v7i3.168

Keywords:

Pituitary, prolactin, macroadenoma, stroke.

Abstract

This is a case report of a 47-year old man with an unknown medical illness, presented with neurological deficits typical of clinical stroke. The Magnetic Resonance Imaging (MRI) findings were an acute left middle cerebral artery (MCA) territory infarction and an incidental finding of a sellar mass likely pituitary origin. The pituitary hormones showed markedly hyperprolactinaemia with the level of 21146 ng/ml (n 4.04 – 15.2 ng/ml), low Follicle-stimulating hormone (FSH) with a level of 0.929 IU/L (n 1.5-12.4 IU/L), and low luteinizing hormone (LH) with a level of 1.11 IU/L (n 1.7-8.6 IU/L). Other investigations of serum cortisol, growth hormone (GH), thyroid-stimulating hormone (TSH), platelet count and coagulation profiles were normal. The patient was treated conservatively in the ward for acute ischaemic stroke and later was started on dopamine agonist cabergoline for hyperprolactinaemia.

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Author Biographies

Wan Mohd Saifuhisam Wan Zain

1Department of Chemical Pathology, School of Medical Sciences, Universiti Sains Malaysia, Jalan Raja Perempuan Zainab 2, 16150 Kota Bharu, Kelantan, Malaysia.
2Hospital Universiti Sains Malaysia, Jalan Raja Perempuan Zainab 2, 16150 Kota Bharu Kelantan, Malaysia

Julia Omar

1Department of Chemical Pathology, School of Medical Sciences, Universiti Sains Malaysia, Jalan Raja Perempuan Zainab 2, 16150 Kota Bharu, Kelantan, Malaysia.
2Hospital Universiti Sains Malaysia, Jalan Raja Perempuan Zainab 2, 16150 Kota Bharu Kelantan, Malaysia

Tuan Salwani Tuan Ismail

1Department of Chemical Pathology, School of Medical Sciences, Universiti Sains Malaysia, Jalan Raja Perempuan Zainab 2, 16150 Kota Bharu, Kelantan, Malaysia.
2Hospital Universiti Sains Malaysia, Jalan Raja Perempuan Zainab 2, 16150 Kota Bharu Kelantan, Malaysia

Nor Azlin Azraini Che Soh Che Soh

1Department of Chemical Pathology, School of Medical Sciences, Universiti Sains Malaysia, Jalan Raja Perempuan Zainab 2, 16150 Kota Bharu, Kelantan, Malaysia.
2Hospital Universiti Sains Malaysia, Jalan Raja Perempuan Zainab 2, 16150 Kota Bharu Kelantan, Malaysia

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Published

2021-09-01
CITATION
DOI: 10.33102/mjosht.v7i3.168
Published: 2021-09-01

How to Cite

Wan Mohd Saifuhisam Wan Zain, Julia Omar, Tuan Salwani Tuan Ismail, & Che Soh, N. A. A. C. S. (2021). Hyperprolactinaemia in a Patient with Acute Ischaemic Stroke. Malaysian Journal of Science Health & Technology, 7(3), 50–53. https://doi.org/10.33102/mjosht.v7i3.168