Headache with Isolated Sixth Cranial Nerve Palsy in an Overweight Woman: A Case of Idiopathic Intracranial Hypertension


Total Views: 30 | Total Downloads: 21

Authors

  • Goe Xian Jeff Emergency Department, Hospital Tuanku Jaafar, Ministry of Health Malaysia, Jalan Rasah, Seremban, 70300, Malaysia.
  • Sharifah Najwa Syed Mohamad Family Medicine Unit, Faculty of Medicine and Health Sciences, Universiti Sains Islam Malaysia, Persiaran Ilmu, Nilai, 71800, Malaysia.
  • Siti Noorfaezah Abdul Kadir Emergency Department, Hospital Tuanku Jaafar, Ministry of Health Malaysia, Jalan Rasah, Seremban, 70300, Malaysia.
  • Syed Hussein Barakbah Emergency Department, Hospital Tuanku Jaafar, Ministry of Health Malaysia, Jalan Rasah, Seremban, 70300, Malaysia.

DOI:

https://doi.org/10.33102/mjosht.v10i1.381

Keywords:

abducens nerve palsy, intracranial hypertension, diplopia, headache

Abstract

Idiopathic intracranial hypertension (IIH), also known as pseudotumour cerebri, has an estimated incidence of 1 to 2 in 100,000 people per year. IIH commonly affects obese young women, where its pathogenesis, however, is not clearly understood. Patients present to the emergency department with a wide array of presentations. In light of this, we present a case of isolated sixth cranial nerve palsy in a non-obese young woman due to IIH in which brain imaging studies showed no abnormality; however, lumbar puncture reveals an opening pressure of more than 50  cmH2O. This case would help to alert physicians to consider IIH as one of the differential diagnoses when encountering such cases, as an uncommon presentation in the non-obese patient, and prompt referral is important to avoid unnecessary delay in the treatment of IIH.

Downloads

Download data is not yet available.

References

McCluskey, G., Mulholland, D. A., McCarron, P., & McCarron, M. O. (2015). Idiopathic intracranial hypertension in the northwest of Northern Ireland: epidemiology and clinical management. Neuroepidemiology, 45(1), 34-39.. DOI: 10.1159/000435919

Crum, O. M., Kilgore, K. P., Sharma, R., Lee, M. S., Spiegel, M. R., McClelland, C. M., ... & Chen, J. J. (2020). Etiology of papilledema in patients in the eye clinic setting. JAMA network open, 3(6), e206625-e206625. DOI: https://doi.org/10.1001/jamanetworkopen.2020.6625

Curry Jr, W. T., Butler, W. E., & Barker, F. G. (2005). Rapidly rising incidence of cerebrospinal fluid shunting procedures for idiopathic intracranial hypertension in the United States, 1988–2002. Neurosurgery, 57(1), 97-108.. DOI: 10.1227/01.neu.0000163094.23923.e5

Lee AG, Wall M. Idiopathic intracranial hypertension (pseudotumor cerebri): Epidemiology and pathogenesis. Available at: https://www.uptodate.com/contents/idiopathic-intracranial-hypertension-pseudotumor-cerebri-epidemiology-and-pathogenesis. (Accessed on 19 April 2022)

Kosmorsky G. S. (2014). Idiopathic intracranial hypertension: pseudotumor cerebri. Headache, 54(2), 389–393. DOI: https://doi.org/10.1111/head.12284

Wall, M., Kupersmith, M. J., Kieburtz, K. D., Corbett, J. J., Feldon, S. E., Friedman, D. I., Katz, D. M., Keltner, J. L., Schron, E. B., McDermott, M. P., & NORDIC Idiopathic Intracranial Hypertension Study Group (2014). The idiopathic intracranial hypertension treatment trial: clinical profile at baseline. JAMA neurology, 71(6), 693–701. DOI: https://doi.org/10.1001/jamaneurol.2014

Qiao, L., & Wei, Y. (2020). Familial idiopathic intracranial hypertension in two non-obese Chinese sisters. Frontiers in Neurology, 11, 569432. DOI: https://doi.org/10.3389/fneur.2020.569432

Donaldson, L., Jhaveri, A., Micieli, J., & Margolin, E. (2022). Idiopathic intracranial hypertension in atypical demographics. Journal of the neurological sciences, 437, 120271. DOI: https://doi.org/10.1016/j.jns.2022.120271

Smith, S. V., & Friedman, D. I. (2017). The Idiopathic Intracranial Hypertension Treatment Trial: A Review of the Outcomes. Headache, 57(8), 1303–1310. DOI: https://doi.org/10.1111/head.13144

Kesserwani H. (2021). Isolated Sixth Nerve Palsy: A Case of Pseudotumor Cerebri and an Overview of the Evolutionary Dynamic Geometry of Dorello's Canal. Cureus, 13(5), e15340. DOI: https://doi.org/10.7759/cureus.15340

Shaw, G. Y., & Million, S. K. (2012). Benign intracranial hypertension: a diagnostic dilemma. Case reports in otolaryngology, 2012, 814696. DOI: https://doi.org/10.1155/2012/814696

Markey, K. A., Mollan, S. P., Jensen, R. H., & Sinclair, A. J. (2016). Understanding idiopathic intracranial hypertension: mechanisms, management, and future directions. The Lancet. Neurology, 15(1), 78–91. DOI: https://doi.org/10.1016/S1474-4422(15)00298-7

Rehder D. (2020). Idiopathic Intracranial Hypertension: Review of Clinical Syndrome, Imaging Findings, and Treatment. Current problems in diagnostic radiology, 49(3), 205–214. DOI: https://doi.org/10.1067/j.cpradiol.2019.02.012

Galgano, M. A., & Deshaies, E. M. (2013). An update on the management of pseudotumor cerebri. Clinical neurology and neurosurgery, 115(3), 252–259. DOI: https://doi.org/10.1016/j.clineuro.2012.11.018

Weiner G (contributing writer). Managing Idiopathic Intracranial Hypertension: The Evidence Builds. (2015) [Internet] EyeNet Magazine; pg29-30. Available at: https://www.aao.org/eyenet/article/managing-idiopathic-intracranial-hypertension-evid. Accessed March 17, 2024.

Published

2024-04-05
CITATION
DOI: 10.33102/mjosht.v10i1.381
Published: 2024-04-05

How to Cite

Goe Xian Jeff, Sharifah Najwa Syed Mohamad, Siti Noorfaezah Abdul Kadir, & Syed Hussein Barakbah. (2024). Headache with Isolated Sixth Cranial Nerve Palsy in an Overweight Woman: A Case of Idiopathic Intracranial Hypertension. Malaysian Journal of Science Health & Technology, 10(1), 69–72. https://doi.org/10.33102/mjosht.v10i1.381

Issue

Section

Medical